Platelet Rich Fibrine PRF
Through skillful, very gentle centrifugation of blood in specially designed tubes, we are able to produce a liquid preparation containing many more platelets than the blood circulating in the blood vessels.
This preparation is called platelet-rich fibrin (PRF- Platelet Rich Fibrin). It is a substance containing many times more platelets than the platelet-rich plasma used so far. Thus, it contains a huge amount of growth factors. You can safely call platelet-rich fibrin “the elixir of youth”.
This is not the end of good news. Additionally, platelet-rich fibrin contains fibrinogen. It is a substance that can polymerize, i.e. join into long threads, creating fibrin. Fibrin, on the other hand, builds network-like spatial structures in which blood platelets bind.
A three-dimensional structure is formed containing a very large number of immobilized platelets, from which growth factors are gradually and slowly released. Compared to platelet-rich plasma, which stimulates tissues for about 12 hours, platelet-rich fibrin remains active at the injection site for up to two weeks. It gradually releases growth factors that continuously regenerate and strengthen the treated tissues.
If the platelet-rich fibrin is injected directly into the skin, after some time needed to activate these factors, the treated area begins to regenerate. The skin becomes more elastic, taut and firm. Small, mesh wrinkles are reduced. Discoloration is reduced and the skin tone is evened out.
Hematopoetic stem cells CD 34 +
Hematopoetic stem cell – HSCs is a cell isolated from the peripheral blood or bone marrow that can differentiate into specialized blood cells. The HSC cell is multipotent as it can differentiate into eight to ten distinct daughter cell lines and has a high multiplication capacity.
Hematopoietic stem cells migrate from the bone marrow to the peripheral blood, but are present in a very small number of 1: 10,000 cells.
All HSC cells show the presence of markers: CD34, CD59, Thy1 and C-kit. The presence of the CD34 marker has become the main distinguishing feature of HSCs, used for their isolation, since it is not present on the surface of fully differentiated blood cells.
It is a group of cells with the greatest regenerative potential, and thanks to the latest centrifugation technology, we are able to increase the number of these cells in the centrifuged preparation.